A CRISPR enhanced Viral Integration Site detection method in genome level

We describe CReVIS-seq, a highly efficient, genome-wide method for detecting viral insertion sites using high-throughput sequencing, which is based on in vitro circularization and subsequent cleavage of genomic DNAs in a CRISPR guide RNA-specific manner.

Citation info: Kim HS. et al. CReVIS-seq: a highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites

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