A CRISPR enhanced Viral Integration Site detection method in genome level
We describe CReVIS-seq, a highly efficient, genome-wide method for detecting viral insertion sites using high-throughput sequencing, which is based on in vitro circularization and subsequent cleavage of genomic DNAs in a CRISPR guide RNA-specific manner.
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(blue: indicator sequences at each ends of comparision range, green: LTR sequence in data)
|Comparison range (R) [?]||Minimum frequency (n) [?]|